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Originally Askew Drugs (upstairs was a motel/hotel becoming a brothel in later years), the building at 2524 McKinney St has had many lives since being built in East Downtown (EaDo) in 1935. It was Bottle Warehouse Liquors, the Axiom in 90's (more on Axiom in Houston Press), a nightclub, and has since been operated as a nightclub/bar under various names like the Orbit Room and Loki Lounge. From a 2014 Loopnet listing (archived link):